Services-Updated – Clinglobal

Preclinical and Clinical Research

In collaboration with Clinvet and with a strong focus on the 3Rs principles, we offer various research models and services to support Production and Companion Animal Species product development:

Product types

- Pharmaceuticals
- Vaccines
- Biopharmaceuticals
- Nutritional
- Nutraceuticals
- Biocides
- Rodenticides
- Pesticides
- Repellency

Study types

- Safety
- Local tolerance
- Residue depletion
- Efficacy and challenge studies
  -in vitro
  -in vivo
  -ex vivo

- ADME
  -Pharmacokinetics
  -Bioequivalence
  -Pharmacodynamics

- Immunogenicity
- Duration of Immunity
- Palatability
- Appetence

Research models

Use the dropdown below to navigate the library of research models, pharmacology, safety, and efficacy studies proposed at our Clinvet sites and at our external partners’ premises.

Please contact us if you cannot find what you are looking for or need additional information on our capabilities.

Species	Category	Model	Pathogen/Agent/Target	Isolate origin	Site location	Notes
Bovine	ADME	Bioequivalence			South Africa, Morocco
Bovine	ADME	Pharmacokinetics			South Africa, Morocco
Bovine	ADME	Residue Depletion			South Africa, Morocco
Bovine	Efficacy	Longterm duration of immunity			South Africa, Morocco, Kenya
Bovine	Safety	Local Tolerance			South Africa, Morocco (2)	2) Pilot Only
Bovine	Safety	Target Animal Safety			South Africa, Morocco (2)	2) Pilot Only
Bovine	Bacteria	Experimental Challenge	Anaplasma centrale		Morocco, Kenya (4)	4) Under development
Bovine	Bacteria	Experimental Challenge	Contagious Bovine Pleuropneumonia (CBPP)		Kenya
Bovine	Bacteria	Experimental Challenge	E. coli K99		Ext. Partner (6)	6) RTI Labs (US)
Bovine	Bacteria	Experimental Challenge	Ehrlichia ruminantium		Morocco, Kenya (4)	4) Under development
Bovine	Bacteria	Experimental Challenge	Leptospira		Ext. Partner (6)	6) RTI Labs (US)
Bovine	Flies	Experimental Challenge	Stomoxys calcitrans	RSA	South Africa
Bovine	Fluke	Experimental Challenge	Fasciola hepatica		Morocco (2)	2) Model validated in caprine, but transferable to bovine
Bovine	Helminths	Experimental Challenge	Haemonchus contortus	RSA	South Africa, Morocco
Bovine	Lice	Experimental Challenge	Bovicola bovis	RSA	South Africa
Bovine	Mosquitoes	Experimental Challenge	Aedes aegypti	RSA/EU	South Africa, Morocco
Bovine	Protozoans	Experimental Challenge	Anaplasma marginale		Morocco, Kenya (4)	4) Under development
Bovine	Protozoans	Experimental Challenge	Babesia bigemina		Morocco
Bovine	Protozoans	Experimental Challenge	Babesia bovis	RSA	South Africa (1), Morocco, Kenya	1) Under development
Bovine	Protozoans	Experimental Challenge	Theileria parva (ECF)		Morocco, Kenya
Bovine	Ticks	Field Study	Amblyoma variegatum	KE	Kenya (4)	4) Natural challenge field trial
Bovine	Ticks	Experimental Challenge	Amblyomma americanum	US	South Africa, Morocco
Bovine	Ticks	Experimental Challenge	Amblyomma hebraeum	RSA	South Africa
Bovine	Ticks	Experimental Challenge	Amblyomma variegatum	Africa	Morocco
Bovine	Ticks	Experimental Challenge	Dermacentor reticulatus	EU	South Africa, Morocco
Bovine	Ticks	Experimental Challenge	Dermacentor variabilis	US	South Africa, Morocco
Bovine	Ticks	Experimental Challenge	Haemaphysalis longicornis	US	South Africa, Morocco
Bovine	Ticks	Experimental Challenge	Hyalomma marginatum		Morocco
Bovine	Ticks	Experimental Challenge	Ixodes ricinus	EU	South Africa, Morocco
Bovine	Ticks	Experimental Challenge	Ixodes scapularis	US	South Africa, Morocco
Bovine	Ticks	Experimental Challenge	Rhipicephalus appendiculatus	RSA	South Africa, Morocco
Bovine	Ticks	Field Study	Rhipicephalus appendiculatus	KE	Kenya (4)	4) Natural challenge field trial
Bovine	Ticks	Experimental Challenge	Rhipicephalus decoloratus	RSA	South Africa, Morocco
Bovine	Ticks	Experimental Challenge	Rhipicephalus evertsi	RSA	South Africa, Kenya (4)	4) Susceptible and resistant isolates
Bovine	Ticks	Experimental Challenge	Rhipicephalus microplus	RSA/BENIN	South Africa, Morocco
Bovine	Ticks	Field Study	Rhipicephalus microplus	KE	Kenya (4)	4) Natural challenge field trial
Bovine	Ticks	Field Study	Rhipicephalus pulchellus	KE	Kenya (4)	4) Natural challenge field trial
Bovine	Trypanosomes	Experimental Challenge	Trypanosoma brucei		South Africa, Morocco
Bovine	Trypanosomes	Experimental Challenge	Trypanosoma congolense		South Africa, Morocco
Bovine	Trypanosomes	Experimental Challenge	Trypanosoma congolense		Kenya (4)	4) Fly Challenge
Bovine	Trypanosomes	Experimental Challenge	Trypanosoma vivax		South Africa, Morocco
Bovine	Trypanosomes	Experimental Challenge	Trypanosoma vivax		Kenya (4)	4) Fly Challenge
Bovine	Virus	Experimental Challenge	Bovine Herpesvirus Type 1- BHV-1		Ext. Partner (6)	6) RTI Labs (US)
Bovine	Virus	Experimental Challenge	Bovine Respiratory Syncytial Virus		Kenya, Ext. Partner (6)	6) RTI Labs (US)
Bovine	Virus	Experimental Challenge	Bovine Viral Diarrhea Virus - Types 1 and 2		Kenya, Ext. Partner (6)	6) RTI Labs (US)
Bovine	Virus	Experimental Challenge	Coronavirus		Ext. Partner (6)	6) RTI Labs (US)
Bovine	Virus	Experimental Challenge	Foot and Mouth Disease (FMD)		Kenya (4), Ext. Partner (6)	4) Immunogenicity only 6) Immunogenicity only
Bovine	Virus	Experimental Challenge	Malignant Catarrhal Fever (MCF)		Kenya
Bovine	Virus	Experimental Challenge	Rift Valley Fever (RVF)		Kenya
Bovine	Virus	Experimental Challenge	Rotavirus		Kenya, Ext. Partner (6)	6) RTI Labs (US)
Camel	Efficacy	Longterm duration of immunity			Kenya (4)	4) Unconfined field trial
Camel	Virus	Field Study	Rift Valley Fever (RVF)		Kenya (4)	4) Natural challenge field trial
Canine	ADME	Bioequivalence			South Africa, Morocco, USA
Canine	ADME	Pharmacokinetics			South Africa, Morocco, USA
Canine	Efficacy	Vaccine challenge			USA
Canine	Efficacy	Immunogenicity			South Africa
Canine	Efficacy	Longterm duration of immunity			South Africa, Morocco, USA
Canine	Others	Palatability			South Africa, Morocco, USA
Canine	Others	Dermatitis model	Flea Induced Dermatitis		South Africa (1)	1) Under development
Canine	Others	Dermatitis model	Atopic Dermatitis		South Africa (1)	1) Under development
Canine	Safety	Target Animal Safety			South Africa, Morocco (2), USA	2) Pilot Only
Canine	Safety	Local Tolerance			South Africa, Morocco (2)	2) Pilot Only
Canine	Bacteria	Experimental Challenge	Bordetella bronchiseptica		USA
Canine	Bacteria	Experimental Challenge	Borrelia burgdorferi	EU/US	Morocco (2), USA	2) Challenge material from field-collected ticks in EU & US
Canine	Bacteria	Experimental Challenge	Leptospira		USA (3)	3) Challenge material supplied by Sponsor
Canine	Fleas	Experimental Challenge	Ctenocephalides felis	EU/US	South Africa, Morocco, USA
Canine	Flies	Experimental Challenge	Phlebotomus perniciosus	EU	Morocco
Canine	Flies	Experimental Challenge	Stomoxys calcitrans	RSA	South Africa
Canine	Helminths	Experimental Challenge	Ancylostoma braziliense	RSA	South Africa, Morocco (2), USA	2) Challenge material to be imported
Canine	Helminths	Natural Infestation	Ancylostoma braziliense	MU	Mauritius (5)	5) Contact us for more information
Canine	Helminths	Natural Infestation	Ancylostoma caninum	MU	Mauritius (5)	5) Contact us for more information
Canine	Helminths	Experimental Challenge	Ancylostoma caninum	US/EU	South Africa, Morocco (2), USA	2) Challenge material to be imported
Canine	Helminths	Experimental Challenge	Angiostrongylus vasorum	EU	Morocco (2)	2) Challenge material to be imported
Canine	Helminths	Natural Infestation	Dipylidium caninum	MU	Mauritius (5)	5) Contact us for more information
Canine	Helminths	Experimental Challenge	Dipylidium caninum	US	South Africa (1), Morocco (2), USA	1) Canine genotype 2) Challenge material to be imported
Canine	Helminths	Experimental Challenge	Dirofilaria immitis	EU/US	Morocco, USA
Canine	Helminths	Experimental Challenge	Echinococcus multilocularis	EU	South Africa
Canine	Helminths	Natural Infestation	Spirocerca lupi	MU	Mauritius (5)	5) Contact us for more information
Canine	Helminths	Experimental Challenge	Spirocerca lupi	RSA	South Africa
Canine	Helminths	Experimental Challenge	Toxascaris leonina	EU/US	South Africa, Morocco (2), USA	2) Challenge material to be imported
Canine	Helminths	Natural Infestation	Toxocara canis	MU	Mauritius (5)	5) Contact us for more information
Canine	Helminths	Experimental Challenge	Toxocara canis	EU/US	South Africa, Morocco (2), USA	2) Challenge material to be imported
Canine	Helminths	Natural Infestation	Trichuris vulpis	MU	Mauritius (5)	5) Contact us for more information
Canine	Helminths	Experimental Challenge	Trichuris vulpis	US	South Africa, Morocco (2), USA	2) Challenge material to be imported
Canine	Helminths	Experimental Challenge	Uncinaria stenocephala	EU/US	South Africa, Morocco, USA
Canine	Mites	Natural Infestation	Demodex spp	RSA	South Africa
Canine	Mites	Experimental Challenge	Otodectes cynotis	RSA	South Africa
Canine	Mites	Natural Infestation	Sarcoptes scabei	RSA	South Africa
Canine	Mosquitoes	Experimental Challenge	Aedes aegypti	RSA/EU/US	South Africa, Morocco, USA
Canine	Mosquitoes	Experimental Challenge	Aedes albopictus	EU	Morocco
Canine	Mosquitoes	Experimental Challenge	Culex quinquefasciatus	RSA	South Africa
Canine	Protozoans	Experimental Challenge	Anaplasma phagocytophilum	EU/US	South Africa, Morocco (2), USA	2) Challenge material from field-collected ticks in US
Canine	Protozoans	Experimental Challenge	Babesia canis	EU	South Africa
Canine	Protozoans	Experimental Challenge	Babesia rossi	RSA	South Africa
Canine	Protozoans	Experimental Challenge	Babesia vogeli	RSA	South Africa, USA
Canine	Protozoans	Experimental Challenge	Ehrlichia canis	RSA	South Africa
Canine	Protozoans	Natural Infection	Leishmania infantum		Morocco (2), Ext. Partner (6)	2) Naturally infected animals for treatment studies at site 6) Exposure of naïve animals to natural challenge. Partner in Greece (EU).
Canine	Ticks	Experimental Challenge	Amblyomma americanum	US	South Africa, Morocco, USA
Canine	Ticks	Experimental Challenge	Amblyomma maculatum	US	USA
Canine	Ticks	Experimental Challenge	Dermacentor reticulatus	EU	South Africa, Morocco
Canine	Ticks	Experimental Challenge	Dermacentor variabilis	US	South Africa, Morocco, USA
Canine	Ticks	Experimental Challenge	Haemaphysalis elliptica	RSA	South Africa
Canine	Ticks	Experimental Challenge	Haemaphysalis longicornis	US	South Africa, Morocco (2), USA	2) Challenge material to be imported
Canine	Ticks	Experimental Challenge	Hyalomma marginatum		Morocco
Canine	Ticks	Experimental Challenge	Ixodes hexagonus	EU	South Africa, Morocco (2)	2) Challenge material to be imported
Canine	Ticks	Experimental Challenge	Ixodes ricinus	EU	South Africa, Morocco (2)	2) Challenge material from field-collected ticks in EU/US
Canine	Ticks	Experimental Challenge	Ixodes scapularis	US	South Africa, Morocco, USA
Canine	Ticks	Experimental Challenge	Rhipicephalus sanguineus	EU/US/AUS	South Africa, Morocco, USA
Canine	Virus	Experimental Challenge	Canine Adeno Virus 2		USA (3)	3) Challenge material supplied by Sponsor
Canine	Virus	Experimental Challenge	Canine Distemper Virus		USA (3)	3) Challenge material supplied by Sponsor
Canine	Virus	Experimental Challenge	Canine Parainfluenza Virus		USA (3)	3) Challenge material supplied by Sponsor
Canine	Virus	Experimental Challenge	Canine Parvovirus		USA (3)	3) Challenge material supplied by Sponsor
Canine	Virus	Experimental Challenge	Infectious Canine Hepatitis Virus		USA (3)	3) Challenge material supplied by Sponsor
Caprine	ADME	Bioequivalence			South Africa, Morocco
Caprine	ADME	Pharmacokinetics			South Africa
Caprine	ADME	Residue Depletion			South Africa, Morocco
Caprine	Efficacy	Immunogenicity			South Africa (1), Kenya	1) Depending on test item
Caprine	Efficacy	Longterm duration of immunity			South Africa, Morocco, Kenya
Caprine	Safety	Local Tolerance			South Africa, Morocco (2)	2) Pilot Only
Caprine	Safety	Target Animal Safety			South Africa, Morocco (2)	2) Pilot Only
Caprine	Bacteria	Experimental Challenge	Contagious Caprine Pleuropneumonia (CCPP)		Kenya
Caprine	Blowflies	Experimental Challenge	Lucilia cuprina	RSA	South Africa
Caprine	Fluke	Experimental Challenge	Fasciola hepatica	UK	Morocco (2)	2) Challenge material to be imported
Caprine	Virus	Experimental Challenge	Peste de Petits Ruminants (PPR)	Ivory Coast	Kenya
Equine	ADME	Bioequivalence			South Africa, Morocco
Equine	ADME	Pharmacokinetics			South Africa, Morocco
Equine	Efficacy	Longterm duration of immunity			South Africa, Morocco
Equine	Safety	Target Animal Safety			South Africa, Ext. Partner (6)	6) Partner (EU)
Equine	Safety	Local Tolerance			South Africa
Equine	Mosquitoes	Experimental Challenge	Aedes aegypti	RSA	South Africa
Equine	Virus	Experimental Challenge	Equine Herpes Virus		South Africa
Feline	ADME	Bioequivalence			South Africa, USA
Feline	ADME	Pharmacokinetics			South Africa, USA
Feline	Efficacy	Vaccine challenge			USA
Feline	Efficacy	Immunogenicity			USA
Feline	Efficacy	Longterm duration of immunity			South Africa, USA
Feline	Others	Palatability			South Africa, USA
Feline	Others	Dermatitis model			South Africa (1)	1) Under development
Feline	Safety	Target Animal Safety			South Africa, USA
Feline	Safety	Local Tolerance			South Africa
Feline	Bacteria	Experimental Challenge	Chlamydophila felis		USA (3)	3) Challenge material supplied by Sponsor
Feline	Fleas	Experimental Challenge	Ctenocephalides felis	EU/US	South Africa, USA
Feline	Helminths	Experimental Challenge	Ancylostoma braziliense	RSA	South Africa, USA
Feline	Helminths	Experimental Challenge	Ancylostoma tubaeforme	US/EU	South Africa, USA
Feline	Helminths	Experimental Challenge	Dipylidium caninum	RSA	South Africa (1)	1) Feline geontype
Feline	Helminths	Experimental Challenge	Dirofilaria immitis	US	USA
Feline	Helminths	Experimental Challenge	Echinococcus multilocularis	EU	South Africa
Feline	Helminths	Experimental Challenge	Toxascaris leonina	EU/US	South Africa, USA
Feline	Helminths	Experimental Challenge	Toxocara cati	EU/US	South Africa, USA
Feline	Mites	Experimental Challenge	Otodectes cynotis	EU	South Africa
Feline	Mosquitoes	Experimental Challenge	Aedes aegypti	RSA/EU/US	South Africa, USA
Feline	Mosquitoes	Experimental Challenge	Culex quinquefasciatus	RSA	South Africa
Feline	Ticks	Experimental Challenge	Amblyomma americanum	US	South Africa
Feline	Ticks	Experimental Challenge	Dermacentor reticulatus	EU	South Africa
Feline	Ticks	Experimental Challenge	Dermacentor variabilis	US	South Africa, USA
Feline	Ticks	Experimental Challenge	Haemaphysalis elliptica	RSA	South Africa
Feline	Ticks	Experimental Challenge	Ixodes ricinus	EU	South Africa
Feline	Ticks	Experimental Challenge	Ixodes scapularis	US	South Africa
Feline	Ticks	Experimental Challenge	Rhipicephalus sanguineus	EU/US	South Africa, USA
Feline	Ticks	Experimental Challenge	Rhipicephalus turanicus	RSA	South Africa
Feline	Virus	Experimental Challenge	Feline Calicivirus		USA (3)	3) Challenge material supplied by Sponsor
Feline	Virus	Experimental Challenge	Feline Leukemia Virus		USA (3)	3) Challenge material supplied by Sponsor
Feline	Virus	Experimental Challenge	Feline Panleukopenia Virus		USA (3)	3) Challenge material supplied by Sponsor
Feline	Virus	Experimental Challenge	Feline Viral Rhinotracheitis		USA (3)	3) Challenge material supplied by Sponsor
in-vitro	Fleas	Contact	Ctenocephalides felis	EU/US	South Africa (1)	1) Motility & mortality assessment
in-vitro	Flies	Membrane feeding	Glossina spp		Kenya (4)	4) Types of studies using membrane feeding: Repellency \| Contact insecticide efficacy \| Systemic insecticide efficacy
in-vitro	Flies	Contact	Glossina spp		Kenya
in-vitro	Flies	Contact & Repellence	Lucilia cuprina	RSA	South Africa
in-vitro	Flies	Contact & Repellence	Musca domestica	RSA	South Africa
in-vitro	Flies	Membrane feeding	Phlebotomus perniciosus	EU	Morocco (2)	2) Under development
in-vitro	Flies	Contact	Phlebotomus perniciosus	EU	Morocco
in-vitro	Flies	Membrane feeding	Stomoxys calcitrans	RSA	South Africa (1)	1) Types of studies using membrane feeding: Repellency \| Contact insecticide efficacy \| Systemic insecticide efficacy
in-vitro	Flies	Contact & Repellence	Stomoxys calcitrans	RSA	South Africa
in-vitro	Flies	Experimental Challenge	Glossina morsitans morsitans (Tsetse)		Kenya
in-vitro	Helminths	Egg hatch & larval development	Haemonchus contortus	RSA	South Africa
in-vitro	Helminths	Egg hatch & larval development	Trichostrongylus colubriformis	RSA	South Africa
in-vitro	Insects	Contact & Repellence	Blatella germanica	RSA	South Africa
in-vitro	Insects	Contact & Repellence	Cimex lectularius	RSA	South Africa
in-vitro	Insects	Contact & Repellence	Formicidae	RSA	South Africa
in-vitro	Insects	Contact & Repellence	Periplaneta americana	RSA	South Africa
in-vitro	Mosquitoes	Membrane feeding	Aedes aegypti	RSA/EU	South Africa, Morocco
in-vitro	Mosquitoes	Contact & Repellence	Aedes aegypti	RSA/EU	South Africa, Morocco
in-vitro	Mosquitoes	Membrane feeding	Aedes albopictus	EU	Morocco
in-vitro	Mosquitoes	Contact & Repellence	Aedes albopictus	EU	Morocco
in-vitro	Mosquitoes	Contact & Repellence	Anopheles quadriannulatus	RSA	South Africa
in-vitro	Mosquitoes	Contact & Repellence	Culex quinquefasciatus	RSA	South Africa
in-vitro	Ticks	Contact (LPT)	Amblyomma americanum	US	South Africa, Morocco
in-vitro	Ticks	Membrane feeding	Amblyomma americanum	US	South Africa (1), Morocco	1) Types of studies using membrane feeding: Repellency \| Contact acaricide efficacy \| Systemic acaricide efficacy \| Speed of transmission study \| Parasite blocking study
in-vitro	Ticks	Contact (LPT)	Dermacentor reticulatus	EU	South Africa, Morocco
in-vitro	Ticks	Membrane feeding	Dermacentor reticulatus	EU	South Africa (1), Morocco	1) Types of studies using membrane feeding: Repellency \| Contact acaricide efficacy \| Systemic acaricide efficacy \| Speed of transmission study \| Parasite blocking study
in-vitro	Ticks	Contact (LPT)	Dermacentor variabilis	US	South Africa, Morocco
in-vitro	Ticks	Membrane feeding	Dermacentor variabilis	US	South Africa (1), Morocco	1) Types of studies using membrane feeding: Repellency \| Contact acaricide efficacy \| Systemic acaricide efficacy \| Speed of transmission study \| Parasite blocking study
in-vitro	Ticks	Contact (LPT)	Ixodes hexagonus	EU	South Africa, Morocco
in-vitro	Ticks	Membrane feeding	Ixodes hexagonus	EU	South Africa (1), Morocco	1) Types of studies using membrane feeding: Repellency \| Contact acaricide efficacy \| Systemic acaricide efficacy \| Speed of transmission study \| Parasite blocking study
in-vitro	Ticks	Contact (LPT)	Ixodes scapularis	EU	South Africa, Morocco
in-vitro	Ticks	Membrane feeding	Ixodes scapularis	EU	South Africa (1), Morocco	1) Types of studies using membrane feeding: Repellency \| Contact acaricide efficacy \| Systemic acaricide efficacy \| Speed of transmission study \| Parasite blocking study
in-vitro	Ticks	Contact (LPT)	Ixodes ricinus	EU	South Africa, Morocco
in-vitro	Ticks	Membrane feeding	Ixodes ricinus	EU	South Africa (1), Morocco (2)	1) Types of studies using membrane feeding: Repellency \| Contact acaricide efficacy \| Systemic acaricide efficacy \| Speed of transmission study \| Parasite blocking study 2) Colony or field-collected ticks in EU/US
in-vitro	Ticks	Contact (LPT)	Rhipicephalus appendiculatus	RSA	South Africa, Morocco
in-vitro	Ticks	Membrane feeding	Rhipicephalus appendiculatus	RSA	South Africa (1), Morocco	1) Types of studies using membrane feeding: Repellency \| Contact acaricide efficacy \| Systemic acaricide efficacy \| Speed of transmission study \| Parasite blocking study
in-vitro	Ticks	Contact (LPT)	Rhipicephalus microplus	RSA	South Africa, Morocco
in-vitro	Ticks	Membrane feeding	Rhipicephalus microplus	RSA	South Africa (1), Morocco	1) Types of studies using membrane feeding: Repellency \| Contact acaricide efficacy \| Systemic acaricide efficacy \| Speed of transmission study \| Parasite blocking study
in-vitro	Ticks	Contact (LPT)	Rhipicephalus sanguineus	EU/US	South Africa, Morocco
in-vitro	Ticks	Membrane feeding	Rhipicephalus sanguineus	EU/US	South Africa (1), Morocco	1) Types of studies using membrane feeding: Repellency \| Contact acaricide efficacy \| Systemic acaricide efficacy \| Speed of transmission study \| Parasite blocking study
in-vivo	Fleas	Rat model	Ctenocephalides felis	EU/US	South Africa
in-vivo	Helminths	Rat model	Trichostrongylus colubriformis	RSA	South Africa
in-vivo	Mosquitoes	Mouse/Rat challenge model	Aedes aegypti	RSA	South Africa
in-vivo	Rodents	Rodenticides models	Mice and Rats		South Africa
in-vivo	Ticks	Rat model	Dermacentor variabilis	US	South Africa
in-vivo	Trypanosomes	Mouse model	Trypanosoma congolense		Morocco
Ovine	ADME	Bioequivalence			South Africa
Ovine	ADME	Pharmacokinetics			South Africa
Ovine	ADME	Residue Depletion			South Africa, Morocco
Ovine	Efficacy	Vaccine challenge	Nairobi Sheep Disease		Kenya
Ovine	Efficacy	Immunogenicity			South Africa (1), Kenya	1) Depending on test item
Ovine	Efficacy	Longterm duration of immunity			South Africa, Morocco, Kenya
Ovine	Safety	Local Tolerance			South Africa, Morocco (2)	2) Pilot Only
Ovine	Safety	Target Animal Safety			South Africa, Morocco (2)	2) Pilot Only
Ovine	Bacteria	Experimental Challenge	Anaplasma phagocytophilum	EU	Morocco
Ovine	Cestodes	Experimental Challenge	Echinococcus granulosus		Morocco (2)	2) Under development
Ovine	Fluke	Experimental Challenge	Fasciola hepatica		Morocco
Ovine	Helminths	Experimental Challenge	Haemonchus contortus	RSA	South Africa, Morocco
Ovine	Helminths	Experimental Challenge	Teladorsagia circumcincta	RSA	South Africa, Morocco
Ovine	Helminths	Experimental Challenge	Trichostrongylus colubriformis	RSA	South Africa, Morocco
Ovine	Lice	Experimental Challenge	Bovicola ovis	RSA	South Africa
Ovine	Mites	Experimental Challenge	Psoroptes ovis	RSA	South Africa
Ovine	Ticks	Experimental Challenge	Amblyomma americanum	US	South Africa, Morocco
Ovine	Ticks	Experimental Challenge	Amblyomma hebraeum	RSA	South Africa, Morocco
Ovine	Ticks	Experimental Challenge	Amblyomma variegatum	Africa	Morocco
Ovine	Ticks	Experimental Challenge	Dermacentor reticulatus	EU	South Africa, Morocco
Ovine	Ticks	Experimental Challenge	Dermacentor variabilis	US	South Africa, Morocco
Ovine	Ticks	Experimental Challenge	Ehrlichia ruminantium		Morocco, Kenya
Ovine	Ticks	Experimental Challenge	Ixodes ricinus	EU	South Africa, Morocco
Ovine	Ticks	Experimental Challenge	Ixodes scapularis	US	South Africa, Morocco
Ovine	Ticks	Experimental Challenge	Rhipicephalus evertsi	RSA	South Africa
Ovine	Virus	Field Study	Rift Valley Fever (RVF)		Kenya (4)	4) Natural challenge field study
Poultry	Efficacy	Field Study			Morocco
Poultry	Bacteria	Experimental Challenge	Campylobacter jejuni		Ext. Partner (6)	6) RTI Labs (US)
Poultry	Bacteria	Experimental Challenge	Salmonella sp		Kenya (4), Ext. Partner (6)	4) Under development 6) RTI Labs (US) & Partner (EU)
Poultry	Protozoans	Experimental Challenge	Coccidiosis		Ext. Partner (6)	6) RTI Labs (US)
Poultry	Virus	Experimental Challenge	Infectious Bronchitis Virus		Ext. Partner (6)	6) RTI Labs (US)
Poultry	Virus	Experimental Challenge	Infectious Bursal Disease Virus		Ext. Partner (6)	6) RTI Labs (US)
Poultry	Virus	Experimental Challenge	Marek's		Ext. Partner (6)	6) RTI Labs (US)
Swine	Bacteria	Experimental Challenge	E. coli post-weaning diarrhea (F18, K88)		Ext. Partner (6)	6) RTI Labs (US)
Swine	Bacteria	Experimental Challenge	Erysipelothrix rhusiopathiae		Ext. Partner (6)	6) RTI Labs (US)
Swine	Bacteria	Experimental Challenge	Mycoplasma hyopneumoniae		Ext. Partner (6)	6) RTI Labs (US)
Swine	Virus	Vaccine challenge	African Swine Fever (ASF)		Kenya (4)	4) Genotypes II and IX
Swine	Virus	Experimental Challenge	Parvovirus		Ext. Partner (6)	6) RTI Labs (US)
Swine	Virus	Experimental Challenge	Porcine circovirus type 2 (PCV2)		Ext. Partner (6)	6) RTI Labs (US)
Swine	Virus	Experimental Challenge	Porcine reproductive and respiratory syndrome (PRRS)		Ext. Partner (6)	6) RTI Labs (US)
Swine	Virus	Experimental Challenge	Swine Influenza		Ext. Partner (6)	6) RTI Labs (US)
Atlantic cod	Bacteria	Experimental Challenge	Francisellosis \| Francisella		Ext. Partner (6)	6) VESO
Atlantic cod	Bacteria	Experimental Challenge	Vibriosis \| Vibrio anguillarum O1		Ext. Partner (6)	6) VESO
Atlantic cod	Bacteria	Experimental Challenge	Vibriosis \| Vibrio anguillarum O2a		Ext. Partner (6)	6) VESO
Atlantic cod	Bacteria	Experimental Challenge	Vibriosis \| Vibrio anguillarum O2b		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Bacterial kidney disease (BKD) \| Renibacterium salmoninarum		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Cold water vibriosis (Hitra disease) \| Vibrio salmonicida		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Enteric redmouth disease (ERM) \| Yersinia ruckeri		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Furunculosis \| Aeromonas salmonicida		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Pasteurellosis \| Pasteurella sp		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Salmon rickettsial syndrome (SRS) \| Piscirickettsia salmonis		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Vibriosis \| Vibrio anguillarum O1		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Vibriosis \| Vibrio anguillarum O2a		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Vibriosis \| Vibrio ordalii		Ext. Partner (6)	6) VESO
Atlantic salmon	Bacteria	Experimental Challenge	Winter ulcers \| Moritella viscosa		Ext. Partner (6)	6) VESO
Atlantic salmon	Parasite	Experimental Challenge	Amoebic gill disease (AGD) \| Paramoeba perurans		Ext. Partner (6)	6) VESO
Atlantic salmon	Parasite	Experimental Challenge	Sea lice \| Lepeophtheirus salmonis		Ext. Partner (6)	6) VESO
Atlantic salmon	Virus	Experimental Challenge	Cardiomyopathy syndrome (CMS) \| Piscine myocarditis virus (PMCV)		Ext. Partner (6)	6) VESO
Atlantic salmon	Virus	Experimental Challenge	Heart and skeletal muscle inflammation (HSMI) \| Piscine orthoreovirus (PRV)		Ext. Partner (6)	6) VESO
Atlantic salmon	Virus	Experimental Challenge	Infectious pancreatic necrosis virus (IPNv)		Ext. Partner (6)	6) VESO
Atlantic salmon	Virus	Experimental Challenge	Infectious salmon anemia virus (ISAv)		Ext. Partner (6)	6) VESO
Atlantic salmon	Virus	Experimental Challenge	Salmon pancreatic disease virus (SPDV - SAV2/3)		Ext. Partner (6)	6) VESO
Atlantic salmon	Parasite	Experimental Challenge	Sea lice / caligus \| Caligus rogercresseyi		Ext. Partner (6)	6) VESO
Coho salmon	Bacteria	Experimental Challenge	Salmon rickettsial syndrome (SRS) \| Piscirickettsia salmonis		Ext. Partner (6)	6) VESO
Lumpfish	Bacteria	Experimental Challenge	Atypical furunculosis \| Atypical Aeromonas salmonicida		Ext. Partner (6)	6) VESO
Lumpfish	Bacteria	Experimental Challenge	Pasteurellosis \| Pasteurella sp		Ext. Partner (6)	6) VESO
Lumpfish	Bacteria	Experimental Challenge	Vibriosis \| Vibrio anguillarum		Ext. Partner (6)	6) VESO
Rainbow trout	Bacteria	Experimental Challenge	Furunculosis \| Aeromonas salmonicida		Ext. Partner (6)	6) VESO
Rainbow trout	Bacteria	Experimental Challenge	Salmon rickettsial syndrome (SRS) \| Piscirickettsia salmonis		Ext. Partner (6)	6) VESO
Rainbow trout	Bacteria	Experimental Challenge	Vibriosis \| Vibrio anguillarum O1		Ext. Partner (6)	6) VESO
Rainbow trout	Bacteria	Experimental Challenge	Vibriosis \| Vibrio anguillarum O2a		Ext. Partner (6)	6) VESO
Rainbow trout	Virus	Experimental Challenge	Infectious pancreatic necrosis virus (IPNv)		Ext. Partner (6)	6) VESO
Seabass	Bacteria	Experimental Challenge	Pasteurellosis \| Photobacterium damselae		Ext. Partner (6)	6) VESO
Seabass	Bacteria	Experimental Challenge	Vibriosis \| Vibrio anguillarum		Ext. Partner (6)	6) VESO
in-vitro	Parasite		Sea lice \| Lepeophtheirus salmonis & Caligus rogercresseyi		Ext. Partner (6)	6) VESO
Species	Category	Model	Pathogen/Agent/Target	Isolate origin

Product Development Services

Program Management

Clinglobal’s program management team comprises animal health professionals, each with over 25 years of experience in veterinary product development. The team can manage entire development programs of novel or enhanced animal care products or assist with leading sections such as ad-hoc model development to proof of concept or pilot to pivotal lab studies.

Clinglobal’s program managers act as the Sponsor’s primary point of contact, coordinate the program activities within the Clinglobal group companies and manage external partners involved in the project.

Through our clinical facilities in South Africa and Morocco and a network of collaborators across the continent, Clinglobal is uniquely positioned to support commercial and research and development programs in Africa.

Regulatory Affairs

The regulatory affairs team at Clinglobal offers comprehensive services to support product development and life cycle management. From regulatory affairs strategy advice to hands-on assistance in the USA, Europe, and other regions, our team is ready to contribute their extensive international experience in Animal Health Regulatory Affairs to advance our customer’s projects.

Quality Assurance

At Clinglobal, quality is paramount. In addition to overseeing process and regulatory compliance of the projects delivered by the group, Clinglobal’s multi-layered Quality Assurance team offers a range of services directly to our customers, including vendor qualification, GCP and GLP compliance audits, training, and more.

Consultancy

Clinglobal’s team of Subject Matter Experts provides scientific and technical guidance to projects run in-house. Our experts offer consultancy services in parasitology and vector-borne diseases; pharmacology and drug safety; molecular biology and immunology; virology, bacteriology, and mycology; vaccine and pharmaceutical product development; and more. In addition, Clinglobal’s network of partners and external consultants broadens this list with geographies and technical specialties addressing almost any project’s needs.

Monitoring

Effective, proactive, and timeous communication is critical for effective decision-making during a clinical trial. Our highly experienced and trained monitors provide the oversite to facilitate the interaction between sponsors and investigators. Our team’s proposed services include monitoring studies conducted at Clinvet or third-party sites according to regulatory requirements and VICH GL9 and assisting third-party suppliers with quality compliance.